Carbamic acid, N-[(1R,2R,5S)-5-[(dimethylamino)carbonyl]-2-[(methylsulfonyl)oxy]cyclohexyl]-, 1,1-dimethylethyl ester
(1R,2R,4S)-2-[(tert-butoxycarbonyl)aMino]-4-[(diMethylaMino)carbonyl]cyclohexyl Methanesulfonate
CAS: 929693-31-2
Molecular Formula: C15H28N2O6S
Carbamic acid, N-[(1R,2R,5S)-5-[(dimethylamino)carbonyl]-2-[(methylsulfonyl)oxy]cyclohexyl]-, 1,1-dimethylethyl ester - Names and Identifiers
Carbamic acid, N-[(1R,2R,5S)-5-[(dimethylamino)carbonyl]-2-[(methylsulfonyl)oxy]cyclohexyl]-, 1,1-dimethylethyl ester - Physico-chemical Properties
| Molecular Formula | C15H28N2O6S |
| Molar Mass | 364.46 |
| Density | 1.21±0.1 g/cm3(Predicted) |
| Boling Point | 546.0±50.0 °C(Predicted) |
| pKa | 11.09±0.60(Predicted) |
Carbamic acid, N-[(1R,2R,5S)-5-[(dimethylamino)carbonyl]-2-[(methylsulfonyl)oxy]cyclohexyl]-, 1,1-dimethylethyl ester - Upstream Downstream Industry
Carbamic acid, N-[(1R,2R,5S)-5-[(dimethylamino)carbonyl]-2-[(methylsulfonyl)oxy]cyclohexyl]-, 1,1-dimethylethyl ester - Introduction
(1R,2R,4S)-2-[(tert-butoxycarbonyl)aMino]-4-[(diMethylaMino)carbonyl]cyclohexyl Methanesulfonate is an organic compound with the following properties:
1. Appearance: The compound is a solid, usually white crystal.
2. Solubility: It is soluble in some organic solvents, such as methanol, dichloromethane and ethanol.
3. Melting Point: its melting point is about 50-55 ° C.
(1R,2R,4S)-2-[(tert-butoxycarbonyl)aMino]-4-[(diMethylaMino)carbonyl]cyclohexyl Methanesulfonate uses:
This compound can be used as an important intermediate in organic synthesis and used to prepare other compounds or drugs. It is commonly used in the pharmaceutical field to synthesize specific amino acid derivatives or polypeptides.
Method:
The synthesis of (1R,2R,4S)-2-[(tert-butoxycarbonyl)aMino]-4-[(diMethylaMino)carbonyl]cyclohexyl Methanesulfonate is usually accomplished by a multi-step reaction. A common synthesis method is to react cyclohexan-1, 2-diol and propionimide to produce cyclohexan-1, 2-dimethyl ether, hydroxymethylation is then carried out with sodium chloromethylsulfonate in methyl chloride to give-(2-hydroxymethyl) cyclohexan-1, 2-dimethyl ether. Next, the amino group is protected, reacted to form the corresponding carboxylic acid ester, and finally treated with methanesulfonic acid to obtain the final product.
Safety Information:
(1R,2R,4S)-2-[(tert-butoxycarbonyl)aMino]-4-[(diMethylaMino)carbonyl]cyclohexyl methanosulfonate should be used in accordance with general laboratory safety procedures. It may be irritating to the eyes, skin and respiratory system. Avoid inhalation or contact with skin. Wear appropriate protective gloves and eye protection during use. If it gets into the eyes or skin, rinse immediately with plenty of water and seek medical advice.
1. Appearance: The compound is a solid, usually white crystal.
2. Solubility: It is soluble in some organic solvents, such as methanol, dichloromethane and ethanol.
3. Melting Point: its melting point is about 50-55 ° C.
(1R,2R,4S)-2-[(tert-butoxycarbonyl)aMino]-4-[(diMethylaMino)carbonyl]cyclohexyl Methanesulfonate uses:
This compound can be used as an important intermediate in organic synthesis and used to prepare other compounds or drugs. It is commonly used in the pharmaceutical field to synthesize specific amino acid derivatives or polypeptides.
Method:
The synthesis of (1R,2R,4S)-2-[(tert-butoxycarbonyl)aMino]-4-[(diMethylaMino)carbonyl]cyclohexyl Methanesulfonate is usually accomplished by a multi-step reaction. A common synthesis method is to react cyclohexan-1, 2-diol and propionimide to produce cyclohexan-1, 2-dimethyl ether, hydroxymethylation is then carried out with sodium chloromethylsulfonate in methyl chloride to give-(2-hydroxymethyl) cyclohexan-1, 2-dimethyl ether. Next, the amino group is protected, reacted to form the corresponding carboxylic acid ester, and finally treated with methanesulfonic acid to obtain the final product.
Safety Information:
(1R,2R,4S)-2-[(tert-butoxycarbonyl)aMino]-4-[(diMethylaMino)carbonyl]cyclohexyl methanosulfonate should be used in accordance with general laboratory safety procedures. It may be irritating to the eyes, skin and respiratory system. Avoid inhalation or contact with skin. Wear appropriate protective gloves and eye protection during use. If it gets into the eyes or skin, rinse immediately with plenty of water and seek medical advice.
Last Update：2024-04-09 18:58:34
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Spot supply
Product Name: Edoxaban Impurity 32 Visit Supplier Webpage Request for quotationCAS: 929693-31-2
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
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Downstream Products for Carbamic acid, N-[(1R,2R,5S)-5-[(dimethylamino)carbonyl]-2-[(methylsulfonyl)oxy]cyclohexyl]-, 1,1-dimethylethyl ester
(5H-Pyrrolo[3,4-d]thiazole-5-carboxylic acid,2-[[[(1R,2S,5S)-2-[[(5-chloro-1H-indol-2-yl)carbonyl]aMino]-5-[(diMethylaMino)carbonyl]cyclohexyl]aMino]carbonyl]-4,6-dihydro-,1,1-diMethylethyl ester
Edoxaban Impurity 16
Edoxaban Impurity 16